Consortium nurtures ex vivo gene therapy firm
نویسندگان
چکیده
منابع مشابه
Ex vivo gene therapy for HIV-1 treatment.
Until recently, progress in ex vivo gene therapy (GT) for human immunodeficiency virus-1 (HIV-1) treatment has been incremental. Long-term HIV-1 remission in a patient who received a heterologous stem cell transplant for acquired immunodeficiency syndrome-related lymphoma from a CCR5(-/-) donor, even after discontinuation of conventional therapy, has energized the field. We review the status of...
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We have examined whether primary human muscle-derived cells can be used in ex vivo gene therapy to deliver BMP-2 and to produce bone in vivo. Two in vitro experiments and one in vivo experiment were used to determine the osteocompetence and BMP-2 secretion capacity of cells isolated from human skeletal muscle. We isolated five different populations of primary muscle cells from human skeletal mu...
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ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 2016
ISSN: 1087-0156,1546-1696
DOI: 10.1038/nbt0616-578